Along with rapid advance in cities and economic structure changes, traditional family structure and concept are changing to affect learning attitudes and behavior quality to result in crises in the operation of healthy society. “Ethical instruction” therefore has become the emphasis of global education in the 21st century. The practice of ethical instruction in life allows students learning the virtue of behavior in life and stressing on the meanings of learning in practice and continued education. Gorgeous pictures, animations, and films presented on computers change children’s learning methods to become easily accepting stimulating information, but not used to reading texts. Apparently, the establishment of digital games plays an important role in learning process. With nonequivalent pretest posttest control group design, 261 students of Beihua University are proceeded 15-week (3 hours per week for total 45 hours) experimental teaching in this study. The research results show significant effects of 1.digital game-based teaching on ethical instruction effectiveness, 2.experiential learning on ethical instruction effectiveness, and 3.digital game-based teaching integrated experiential learning on the promotion of ethical instruction effectiveness. According to the results, suggestions are proposed, expecting to guide learners solving problems in games so that students could solve problems by themselves to achieve autonomous learning. Besides, it allows students experiencing and learning in situations, establishing good ethics to change the attitudes and behaviors in similar situations in the future, and cultivating the concepts of responsibility, respect, concern, helping each other, cooperation, and bravery as well as healthy personality.